3-(7-Methoxy-β-carbolin-1-yl)propionic acid monohydrate
نویسندگان
چکیده
In the title compound, C(15)H(14)N(2)O(3)·H(2)O [systematic name: 3-(7-meth-oxy-9H-pyrido[3,4-b]indol-1-yl)propanoic acid monohydrate], the fused rings make dhedral angles of 0.4 (1), 1.1 (2) and 1.4 (2)°. In the crystal, the water mol-ecule is involved in the formation of three independent hydrogen-bonded chains via O-H⋯O and N-H⋯O hydrogen bonds, while the carb-oxy group forms an inter-molecular O-H⋯N hydrogen bond.
منابع مشابه
(S,Z)-3-Phenyl-2-[(1,1,1-trichloro-7-methoxy-2,7-dioxohept-3-en-4-yl)amino]propanoic acid monohydrate
In the title compound, C17H18Cl3NO5·H2O, intra-molecular N-H⋯O and C-H⋯Cl hydrogen bonds form S(6) and S(5) ring motifs, respectively. The chiral organic mol-ecule is connected to the solvent water mol-ecule by a short O-H⋯O hydrogen bond. In the crystal, a weak C-H⋯Cl inter-action connects the organic mol-ecules along [100] while the water mol-ecules act as bridges between the organic mol-ecul...
متن کامل6-Methoxy-1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-9H-β-carbolin-2-ium acetate
In the title compound, C(19)H(21)N(2)O(2) (+)·C(2)H(3)O(2) (-), the 1H-indole ring system is essentially planar [maximum deviation = 0.0257 (14) Å] and forms a dihedral angle of 87.92 (7) Å with the benzene ring attached to the tetra-hydro-pyridinium fragment. The tetra-hydro-pyridinium ring adopts a half-chair conformation. In the crystal, cations and anions are linked by inter-ionic N-H⋯O, C-...
متن کاملCharacterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters.
Zonampanel monohydrate (YM872; [2,3-dioxo-7-(1H-imidazol-1-yl)-6-nitro-1,2,3,4-tetrahydro-1-quinoxalinyl]acetic acid monohydrate) is a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor antagonist. The major elimination route for zonampanel has been reported to be by urine via the kidneys. The purpose of this study is to elucidate the molecular mechanism of the renal...
متن کاملN-(4-Chlorophenyl)-4-methoxy-3-(propanamido)benzamide cyclohexane hemisolvate
The title compound, C(17)H(17)ClN(2)O(3)·0.5C(6)H(12), was prepared by the condensation reaction of 4-meth-oxy-3-(propanamido)-benzoic acid with 4-chloro-aniline. The Cl atom, the propionyl CH(3) group and the cyclo-hexyl CH(2) group are disordered over two sets of sites of equal occupancy in both mol-ecules. The cyclo-hexane solvent mol-ecule is disordered over two orientations which were mode...
متن کامل(R)-2-Benzyl-4-methylpentyl (R)-2-methoxy-2-(1-naphthyl)propionate
The relative configuration of the alcohol component in the title ester, C(27)H(32)O(3), has been assigned as (R) from the known configuration of (R)-(-)-2-meth-oxy-2-(1-naphth-yl)propionic acid [(R)-MαNP acid]. In the crystal structure, the C atom of the methyl group of the MαNP acid lies in the extended plane of the naphthyl ring system [methyl C atom deviates from plane by 0.211 (2) Å; r.m.s....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2011